以来 is read as いらい (irai) and means since.
いらい
irai
そのときいらい
since that time
いちべついらい
since our last meeting
あれいらい
since then
それいらい
ものごころついていらい
for as long as one can remember
ゆうしいらい
since the dawn of history
じんむいらい
since the era of the Emperor Jimmu
かいびゃくいらい
since the beginning of the world
いか
including ...
いぜん
before
いご
after this
いじょう
that's all